Ask The Expert On Demand Webinar: New Paradigms in Intracranial Neuromodulation for Epilepsy-Ask The Expert On Demand Webinar: New Paradigms in Intracranial Neuromodulation for Epilepsy

Ask The Expert On Demand Webinar: New Paradigms in Intracranial Neuromodulation for Epilepsy

Video Transcription

Video Summary

The webinar focused on new paradigms in intracranial neuromodulation for epilepsy, exploring both responsive neurostimulation (RNS) and deep brain stimulation (DBS) applications. Dr. Chen Wu introduced the session, emphasizing the objective to review, evaluate, and discuss different neuromodulation techniques for epilepsy. Dr. Patricia Dugan discussed combining RNS with surgical resection and/or laser ablation, highlighting its use in treating large neocortical seizure foci and regional epilepsy. She explained the recording and stimulation capabilities of RNS, which allow for monitoring brain activity and aborting seizures in real-time. Dr. Jamie Van Gumpel highlighted the potential of targeting the anterior nucleus (ANT) and centromedian nucleus (CM) of the thalamus with DBS for treating multifocal and generalized epilepsy. He detailed that ANT-DBS is beneficial for temporal and frontal seizures, while CM-DBS shows promise for generalized seizures, like those seen in Lennox-Gastaut syndrome. The discussion also touched on the personalization of stimulation parameters, noting the necessity for more studies to optimize treatment efficacy. Participants were encouraged to consider patient-specific needs when choosing between RNS and DBS, underlining the importance of treating epilepsy as a network disorder.

Keywords

intracranial neuromodulation

epilepsy

responsive neurostimulation

deep brain stimulation

surgical resection

laser ablation

anterior nucleus

centromedian nucleus

personalization of stimulation